Topics

  • Biological ontologies
  • Orthologs, paralogs, inparalogs, outparalogs, ...  
  • Similarity-based function prediction
  • Phylogenomic inference
  • Context-based function prediction
  • Network based function prediction
  • Functional modules
  • Pseudogenes
  • Identification of functionally important residues
  • Structure-function relationships in proteins
  • Practical limits of function prediction
  • Horizontal gene transfer
  • Reconstruction of metabolic pathways
  • Disease-relevant mutations: analysis and prediction 
  • Alternative splicing and protein function 
  • Post-translational modificatiions