General information

This lecture course, accompanied by a practical exersise, is being offered both in winter and summer semester in Weihenstephan. It is suitable for biology students of the 5th semester and higher.

Recommended reading

  • Zvelebil, M. and Baum, J. Introduction to bioinformatics. Garland Science, 2007.
  • Mount, D. Bioinformatics: Sequence and Genome Analysis. Cold Spring Harbor Laboratory Press; 2 edition, 2004.

 

List of topics in winter semester

  • Nucleic acids
  • Protein structure
  • Sequence alignment
  • Sequence motifs
  • Database searches
  • Protein folding and structure prediction
  • Homology modeling
  • Protein structure comparison
  • Structure classification
  • Secondary structure prediction
  • Prediction of transmembrane regions
  • Genome analysis
  • Gene prediction
  • RNA structure prediction

List of topics in summer semester

 

  • Low complexity sequences
  • Disordered proteins
  • Protein interactions
  • Molecular evolution
  • Structure-function relationships in proteins
  • Functionally important residues
  • SNPs
  • Alternative splicing
  • microRNAs
  • Annotation, ontologies
  • Threading
  • Repeats
  • Isochores
  • Repeats
  • Pseudogenes
  • Operons