Methods of genome analysis

General information

 

This lecture course, accompanied by a practical exersise, is being offered in summer semester. It is suitable for bioinformatics students of the 4th semester and higher. For students taking Bioinformatics as a minor subject lecture courses "Inroduction to bioinformatics I and II" are a prerequisite for participation in this course.

 

Recommended reading

 

  • Mount, D. Bioinformatics: Sequence and Genome Analysis, second edition. Cold Spring Harbor Laboratory Press, 2004.
  • Pevsner, J. Bioinformatics and Functional Genomics, John Wiley, 2003.
  • Brown, T.A. Genomes 3, Garland Science, 2007.
  • Barnes, M. Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data, second edition. John Wiley, 2007.
  • Lesk, A. Introduction to Genomics, Oxford University Press, 2007

 

List of topics

 

  • Genome analysis: an overview

  • Signals in DNA

  • Gene prediction in prokaryotes

  • Introduction to operons

  • Promoter prediction

  • Operon prediction

  • Gene prediction in eukaryotes

  • Isochores

  • Alternative splicing

  • SNP

  • tRNA, ncRNA

  • microRNA

  • Repeats

  • Pseudogenes