The PEDANT Genome Database contains automatically generated annotation of nearly 500 genomes by a variety of bioinformatics methods. Extensive graphical user interface, multiple functional and structural categories, detailed gene reports, DNA and Protein viewers, genome comparison.
Manually curated high-quality PPI data collected from the scientific literature by expert curators.
Prediction of interacting protein domains based on several computational methods as well as on experimental data.
Isochore assignments are made by several established techniques as well as by a consensus method. Confidence scores are also provided. Manuscript in preparation.
Automate standard tasks in comparative proteomics. PROMPT is a comprehensive bioinformatics software environment which enables the user to compare arbitrary protein sequence sets, revealing statistically significant differences in their annotation features.
A database of alpha-helical membrane protein families obtained by sequence clustering at three hierarchical levels: fold, function, and modeling distance.
HelixCorr is a software to predict correlated mutations specifically for the transmembrane parts of membrane proteins. It includes predictions obtained by several individual prediction algorithms and combines them to a consensus prediction.
Neural network based predictor for helix-helix contacts in alpha-helical membrane proteins.
Currently contains three independent methods to predict experimental behaviour of proteins listed below.
MemEx: Predict the amenability of membrane proteins to cloning, expression, and solubilization
Predict solubility of globular proteins
A sequence-based approach to classify proteins into crystallizable and noncrystallizable
Software for secondary structure assignment in proteins from known atomic coordinates plus a database of STRIDE assignments for all PDB structures
ORPHEUS: Gene prediction in prokaryotic genomes